NON-ADHERENCE TO ANTI-DIABETIC MEDICATIONS AMONG DIABETES PATIENTS ATTENDING DIABETES CLINIC AT KISENYI HEALTH CENTER IV, KAMPALA DISTRICT, A Cross-Sectional STUDY.
DOI:
https://doi.org/10.51168/sjhrafrica.v6i6.1551Keywords:
Non-adherence, Antidiabetic medications, Kisenyi Health Centre IVAbstract
Background
Non-adherence to anti-diabetic medications among diabetes patients poses significant challenges to effective diabetes management, yet many patients fail to take their medications consistently. This study aimed to identify socio-economic, individual, and health facility factors contributing to non-adherence to anti-diabetic medications among diabetes patients attending the diabetic clinic at Kisenyi Health Center IV.
Methodology
A descriptive cross-sectional study design was used, involving 30 diabetes patients selected through simple random sampling. Data was collected using structured questionnaires, and analysis involved descriptive statistics to assess the influence of various factors on medication adherence, with results presented in the form of figures, tables, and pie charts.
Results
The study involved more males, 25 (83%), than females, 5 (17%), the majority of whom were aged between 31 to 45 years, and the least, 1(3%), were aged 61 and above. Findings indicated that socio-economic factors, including limited income (73%) and unemployment (80%), negatively affected adherence. Individual factors such as forgetfulness (57%) and concerns about side effects (80%) contributed to non-adherence. Health facility-related factors, including long waiting times (70%) and limited availability of follow-up appointments (80%), further discouraged adherence among patients. Additionally, 53% reported insufficient patient education programs, which negatively influenced adherence.
Conclusion
There was a complex interplay of socioeconomic, individual, and health facility-related factors contributing to this issue, including medium household income, proximity to the health facility, infrequent transportation problems, forgetfulness, and experiencing side effects that negatively affected adherence.
Recommendation
Enhanced patient education, improved patient-provider communication, and efficient clinic management practices to mitigate barriers to adherence and support diabetes management at Kisenyi Health Center IV.
References
Abate, T. W., Dessie, G., Workineh, Y., Gedamu, H., Birhanu, M., Ayalew, E., ... & Endalamaw, A. (2021). Non-adherence to self-care and associated factors among diabetes adult population in Ethiopia: A systemic review with meta-analysis. PloS one, 16(2), e0245862. https://doi.org/10.1371/journal.pone.0245862
Acharya, A. S., Gupta, E., Prakash, A., & Singhal, N. (2019). Self-reported adherence to medication among patients with type II diabetes mellitus attending a tertiary care hospital in Delhi. J Assoc Physicians India, 67, 26-9.
Aditama, L., Athiyah, U., Utami, W., & Rahem, A. (2019). Adherence behavior assessment of oral Antidiabetic medication use: a study of patient decisions in long-term disease management in primary health care centers in Surabaya. Journal of Basic and Clinical Physiology and Pharmacology, 30(6), 20190257.
Agyemang, C., Van Der Linden, E. L., & Bennet, L. (2021). Type 2 diabetes burden among migrants in Europe: Unravelling the causal pathways. Diabetologia, 64(12), 2665-2675. https://doi.org/10.1007/s00125-021-05586-1
Al-Jaber, H. I., Abu Zarga, M. H., Al-Aboudi, A. F., Al-Qudah, M. A., Al-Shawabkeh, A. F., Abaza, I. F., ... & Afifi, F. U. (2018). Essential oil composition and anticholinesterase activity evaluation of Achillea fragrantissima growing wild in Jordan. Journal of Herbs, Spices & Medicinal Plants, 24(3), 272-281. https://doi.org/10.1080/10496475.2018.1463933
Aminde, L. N., Tindong, M., Ngwasiri, C. A., Aminde, J. A., Njim, T., Fondong, A. A., & Takah,
N. F. (2019). Adherence to anti-diabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon. BMC Endocrine Disorders, 19(1), 1-9. https://doi.org/10.1186/s12902-019-0360-9
Birabwa, C., Bwambale, M. F., Waiswa, P., & Mayega, R. W. (2019). Quality and barriers of outpatient diabetes care in rural health facilities in Uganda - a mixed methods study. BMC Health Services Research, 19(1), 706. https://doi.org/10.1186/s12913-019-4535-x https://doi.org/10.1186/s12913-019-4535-x
Bhattarai, B., Bista, B., Shrestha, S., Budhathoki, B., & Dhamala, B. (2019). Contributing factors of Non-adherence to treatment among patients with type II diabetes mellitus. Journal of Manmohan Memorial Institute of Health Sciences, 5(1), 68-78. https://doi.org/10.3126/jmmihs.v5i1.24075
Boshe, B. D., Yimar, G. N., Dadhi, A. E., & Bededa, W. K. (2021). The magnitude of non-adherence and contributing factors among adult outpatients with diabetes mellitus in Dilla University Referral Hospital, Gedio, Ethiopia. PLoS One, 16(3), e0247952. https://doi.org/10.1371/journal.pone.0247952
Demoz, G. T., Wahdey, S., Bahrey, D., Kahsay, H., Woldu, G., Niriayo, Y. L., & Collier, A. (2020). Predictors of poor adherence to antidiabetic therapy in patients with type 2 diabetes: a cross-sectional study insight from Ethiopia. Diabetology & Metabolic Syndrome, 12, 1-8. https://doi.org/10.1186/s13098-020-00567-7
Ding, Q., Hu, Y., Fu, Y., & Qian, L. (2021). Systematic review and meta-analysis of the correlation between intestinal flora and gestational diabetes mellitus. Annals of Palliative Medicine https://doi.org/10.21037/apm-21-2061
Vol 10, No 9 (September 29, 2021): Annals of Palliative Medicine. https://apm.amegroups.org/article/view/79171
Dzansi, G., Tornu, E., & Chipps, J. (2020). Promoters and inhibitors of treatment adherence among HIV/AIDS patients receiving antiretroviral therapy in Ghana: Narratives from an underserved population. PloS one, 15(3), e0230159. https://doi.org/10.1371/journal.pone.0230159
Huang, I., Lim, M. A., & Pranata, R. (2020). Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia - A systematic review, meta-analysis, and meta-regression. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(4), 395-403. https://doi.org/10.1016/j.dsx.2020.04.018 https://doi.org/10.1016/j.dsx.2020.04.018
Kisigo, G. A., Mcharo, O. C., Robert, J. L., Peck, R. N., Sundararajan, R., & Okello, E. S. (2022). Understanding barriers and facilitators to clinic attendance and medication adherence among adults with hypertensive urgency in Tanzania. PLOS Global Public Health, 2(8), e0000919. https://doi.org/10.1371/journal.pgph.0000919
Kiguli, "J., Alvesson, H. M., Mayega, R. W., Kasujja, F. X., Muyingo, A., Kirunda, B., et al. (2019). "Dietary patterns and practices in rural eastern Uganda.
Mitiku, Y., Belayneh, A., Tegegne, B. A., Kebede, B., Abebe, D., Biyazin, Y., ... & Getachew, M. (2022). Prevalence of medication non-adherence and associated factors among diabetic patients in a tertiary hospital at Debre Markos, Northwest Ethiopia. Ethiopian Journal of Health Sciences, 32(4), 755-764. https://doi.org/10.4314/ejhs.v32i4.12
Murwanashyaka, J. D. D., Ndagijimana, A., Biracyaza, E., Sunday, F. X., & Umugwaneza, M. (2022). Non-adherence to medication and associated factors among type 2 diabetes patients at Clinique Medicale Fraternite, Rwanda: a cross-sectional study. BMC Endocrine Disorders, 22(1), 219. https://doi.org/10.1186/s12902-022-01133-0
Omotosho, T. O. A., & Senghore, T. (2024). Factors influencing therapeutic non-adherence behavior among patients with type 2 diabetes in two public hospitals in the Gambia: A cross-sectional study. Diabetes, Metabolic Syndrome and Obesity, 2683-2692. https://doi.org/10.2147/DMSO.S464761
Owolabi, E. O., & Ajayi, A. I. (2024). Adherence to medication, dietary and physical activity recommendations: Findings from a multicenter cross-sectional study among adults with diabetes in rural South Africa. Journal of Evaluation in Clinical Practice. https://doi.org/10.1111/jep.14035
Siraj, J., Abateka, T., & Kebede, O. (2021). Patients' adherence to anti-diabetic medications and associated factors in Mizan-Tepi University Teaching Hospital: a cross-sectional study. INQUIRY: The Journal of Health Care Organization, Provision, and Financing, 58, 00469580211067477. https://doi.org/10.1177/00469580211067477
Treadwell, M. J., Makani, J., Ohene-Frempong, K., Ofori-Acquah, S., McCurdy, S., de Vries, J., Bukini, D., Dennis-Antwi, J., Kamga, K. K., Mbekenga, C., Wonkam, E. T., Tangwa, G., Royal, C. D., Wonkam, A., & as members of the H3Africa Consortium. (2017). Stakeholder Perspectives on Public Health Genomics Applications for Sickle Cell Disease: A Methodology for a Human Heredity and Health in Africa (H3Africa) Qualitative Research Study. OMICS: A Journal of Integrative Biology, 21(6), 323-332. https://doi.org/10.1089/omi.2017.0047 https://doi.org/10.1089/omi.2017.0047
Upamali, S., & Rathnayake, S. (2023). Perspectives of older people with uncontrolled type 2 diabetes mellitus towards medication adherence: A qualitative study. PLoS One, 18(8), e0289834. https://doi.org/10.1371/journal.pone.0289834
World Health Organization. Vision 2020: The Right to Sight. Global initiative for the elimination of avoidable blindness: action plan 2006-2011. Geneva (CH): World Health Organization; 2016. [2022 Jul 12; ].
World Health Organization. (2003). Adherence to long-term therapies: evidence for action. World Health Organization. https://iris.who.int/handle/10665/42682
Wong, J.S. and Burton, T.A. (1965) Some Properties of Solution of. Monatshefte für Mathematik, 69, 364-674. https://doi.org/10.1007/BF01297623
Xu, N., Xie, S., Chen, Y., Li, J., & Sun, L. (2020). Factors influencing medication non-adherence among Chinese older adults with diabetes mellitus. International Journal of Environmental Research and Public Health, 17(17), 6012 https://doi.org/10.3390/ijerph17176012
Zheng, Y., Ley, S. H., & Hu, F. B. (2018). Global etiology and epidemiology of type 2 diabetes mellitus and its complications. Nature Reviews Endocrinology, 14(2), 88-98. https://doi.org/10.1038/nrendo.2017.151
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Richard Bahangondi, Habert Mpamize, Jane Frank Nalubega, Immaculate Prosperia Naggulu
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
