CORRELATION OF AMNIOTIC FLUID INDEX VALUES WITH MATERNAL AND PERINATAL OUTCOMES IN PRETERM PREMATURE RUPTURE OF MEMBRANES.

Vamsi  Priya; Varada  Hasamnis; Munukutla  Vaidehi

doi:10.51168/sjhrafrica.v6i3.1681

Authors

Vamsi Priya Assistant Professor, Department of Obstetrics and Gynaecology, Rangaraya Medical College, Kakinada, Andhra Pradesh, India.
Varada A Hasamnis Senior Resident, Department of Obstetrics and Gynaecology, Konaseema Institute of Medical Sciences and Research Foundation, Amalapuram, Andhra Pradesh, India.
Munukutla Vaidehi Assistant Professor, Department of Obstetrics and Gynaecology, Konaseema Institute of Medical Sciences, Amalapuram, Andhra Pradesh,

DOI:

https://doi.org/10.51168/sjhrafrica.v6i3.1681

Keywords:

Preterm Premature Rupture of Membranes, Amniotic Fluid Index, Chorioamnionitis, Neonatal Sepsis, Respiratory Distress Syndrome, Neonatal Death, Gestational Age, Obstetrics

Abstract

Background:

Preterm Premature Rupture of Membranes (PPROM) is a significant obstetric complication associated with adverse neonatal outcomes. This study aims to evaluate the relationship between Amniotic Fluid Index (AFI) levels and clinical outcomes in patients with PPROM between 26–36 weeks of gestation.

Methods:

A cohort of 100 patients diagnosed with PPROM between 26–36 weeks of gestation were analyzed. Demographic data, gestational age, AFI levels, and clinical outcomes including chorioamnionitis, neonatal sepsis, respiratory distress syndrome (RDS), and neonatal survival were recorded. Statistical analysis was conducted to assess the associations between AFI levels and these clinical outcomes.

Results:

The study population consisted of 80% patients with gestational ages between 32–36 weeks and 20% between 26–31 weeks. The majority (49%) had an AFI <5. Chorioamnionitis was present in 50%, and neonatal sepsis occurred in 68% of neonates. Neonatal survival was observed in 93% of cases. Gestational age was inversely correlated with AFI (P < 0.001), with lower gestational age associated with AFI <5. No significant association was found between AFI and chorioamnionitis or neonatal sepsis. AFI <5 was significantly associated with an increased risk of RDS (P = 0.003) and neonatal death (P = 0.005), with an odds ratio of 3.78 for RDS in patients with AFI <5. Chorioamnionitis was associated with neonatal sepsis (P = 0.005).

Conclusion:

Low AFI (<5) in patients with PPROM is significantly associated with adverse neonatal outcomes, including respiratory distress syndrome and neonatal death. Gestational age and AFI levels play crucial roles in predicting neonatal survival and complications. Monitoring AFI can help identify high-risk pregnancies requiring closer observation and management.

Recommendations:

Healthcare providers should monitor AFI regularly in PPROM cases, especially with low AFI (<5). Enhanced neonatal surveillance for RDS and other complications is crucial. Early interventions and NICU preparation, particularly for gestational age <32 weeks,

Author Biographies

Vamsi Priya, Assistant Professor, Department of Obstetrics and Gynaecology, Rangaraya Medical College, Kakinada, Andhra Pradesh, India.

Dr. Vamsi Priya is an Assistant Professor of Obstetrics and Gynaecology at Rangaraya Medical College, Kakinada, Andhra Pradesh, India. She completed her MBBS from Rajiv Gandhi Institute of Medical Sciences, Srikakulam, and went on to pursue an M.S. in Obstetrics and Gynaecology from Konaseema Institute of Medical Sciences (KIMS). Dr. Priya further specialized in Reproductive Medicine by completing a Fellowship in Reproductive Medicine (FRM) from Rao Hospital under MGR University, Tamil Nadu. With over six years of experience in clinical practice and teaching, she has authored two publications in her field, contributing significantly to the advancement of Obstetrics and Gynaecology. Dr Vamsi Priya https://orcid.org 0000-0002-9605-4921

Varada A Hasamnis, Senior Resident, Department of Obstetrics and Gynaecology, Konaseema Institute of Medical Sciences and Research Foundation, Amalapuram, Andhra Pradesh, India.

Dr. Varada A Hasamnis is a Senior Resident at Konaseema Institute of Medical Sciences and Research Foundation, Amalapuram, Andhra Pradesh, India. She completed her MBBS from Dr. DY Patil Medical College, Navi Mumbai, Maharashtra, India. Dr. Hasamnis holds a Diploma in Obstetrics and Gynaecology from Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India. She further pursued her Fellowship in Midwifery and Diploma in Family Planning from the College of Physicians and Surgeons, Mumbai, Maharashtra, India. With over 20 years of clinical experience, Dr. Hasamnis has contributed significantly to the field of Obstetrics and Gynaecology. She has authored 15 publications, showcasing her expertise and dedication to advancing women's healthcare. Dr. Varada Hasamnis https://orcid.org 0009-0002-8860-7183

Munukutla Vaidehi, Assistant Professor, Department of Obstetrics and Gynaecology, Konaseema Institute of Medical Sciences, Amalapuram, Andhra Pradesh,

Dr. Munukutla Vaidehi is an Assistant Professor of Obstetrics and Gynaecology at Konaseema Institute of Medical Sciences, Amalapuram, Andhra Pradesh, India. She completed her MBBS from Osmania Medical College, Hyderabad, and her M.S. in Obstetrics and Gynaecology from Rangaraya Medical College, Kakinada. With over 5 years of clinical experience and more than 1 year of teaching experience, Dr. Vaidehi has made valuable contributions to the field of Obstetrics and Gynaecology. Dr. Munukutla Vaidehi https://orcid.org 0009-0007-5511-3968

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