Comparative Efficacy of Dexamethasone Plus Bupivacaine versus Bupivacaine Alone in Ultrasound-Guided Supraclavicular Brachial Plexus Block for Upper Limb Surgeries: A Prospective Non-Randomized Controlled Clinical Trial.
DOI:
https://doi.org/10.51168/sjhrafrica.v7i3.2540Keywords:
bupivacaine, dexamethasone, supraclavicular brachial plexus block, ultrasound guidance, upper limb surgeryAbstract
Background:
Ultrasound-guided supraclavicular brachial plexus block is a dependable technique for upper limb surgery and offers airway-sparing anesthesia. Because plain bupivacaine provides limited postoperative analgesia, adjuncts that hasten onset and prolong block duration remain clinically relevant.
Objectives:
To compare the onset and duration of sensory and motor block produced by 0.5% bupivacaine with 4 mg dexamethasone versus 0.5% bupivacaine alone for supraclavicular brachial plexus block.
Methods:
This prospective comparative clinical study enrolled 60 patients aged 15-70 years with ASA physical status I/II undergoing elbow, forearm, hand, or finger surgery. Patients received an ultrasound-guided supraclavicular block with 24 mL of 0.5% isobaric bupivacaine plus 1 mL dexamethasone (Group D) or 1 mL normal saline (Group P). One patient in Group P dropped out, leaving 30 and 29 patients for analysis. Sensory onset, motor onset, recovery times, surgery duration, and perioperative complications were recorded.
Results:
Group D showed significantly faster sensory onset (3.23 ± 1.28 vs 8.21 ± 2.58 min) and motor onset (6.23 ± 2.31 vs 13.55 ± 2.85 min). Motor recovery (19.73 ± 5.21 vs 6.03 ± 1.23 h) and sensory recovery (23.38 ± 5.99 vs 6.88 ± 1.22 h) were markedly prolonged in Group D; all comparisons were statistically significant. Surgery duration was similar between groups. No drug-related, hemodynamic, neurologic, or procedural complications were documented; one patient in Group P required midazolam for intraoperative anxiety.
Conclusion:
Perineural dexamethasone added to bupivacaine improved block quality by accelerating onset and prolonging sensory and motor blockade in ultrasound-guided supraclavicular brachial plexus block.
Recommendations:
This combination can be considered for upper limb procedures when prolonged postoperative analgesia is desirable, provided patient selection, sterile technique, and postoperative monitoring are maintained.
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