Evaluation of nutritional status and its impact on pulmonary infections in pediatric patients: A hospital-based prospective observational study.
DOI:
https://doi.org/10.51168/sjhrafrica.v7i3.2515Keywords:
Pediatric, undernutrition, pneumonia, bronchopneumonia, lower respiratory tract infection, hospitalizationAbstract
Background:
Pulmonary infections remain a leading cause of pediatric morbidity and hospitalization in low- and middle-income settings, and undernutrition amplifies susceptibility to severe disease and complications.
Objectives:
To evaluate the nutritional status of children admitted with pulmonary infections and to examine its association with infection patterns and short-term clinical outcomes.
Methods:
A hospital-based observational study was conducted in one hundred children aged 1–14 years presenting with clinically diagnosed pulmonary infections. Anthropometry was recorded at admission, and nutritional status was categorized using age-appropriate indices. Pulmonary infection type and severity indicators (severe infection, duration of hospitalization, need for intravenous therapy, and complications) were documented. Group comparisons between children with normal nutrition and undernutrition were performed.
Results:
The mean age was 6.4 ± 3.1 years, and 56% were boys. Undernutrition was present in 58% of children, including mild, moderate, and severe undernutrition in 18%, 26%, and 14%, respectively. Pneumonia was the most common infection pattern, observed in 52% of cases, followed by bronchopneumonia in 28% and recurrent lower respiratory tract infection in 14%. The distribution of infection type did not show a statistically significant association with nutritional status (χ²=3.99, df=3, p=0.263). However, severe infection was significantly more frequent among undernourished children than normally nourished children (55.2% vs 23.8%; χ²=9.84, df=1, p=0.002). Complications were also higher in the undernourished group (34.5% vs 14.3%; χ²=5.16, df=1, p=0.023). Mean hospital stay was significantly longer among undernourished children (7.1 ± 2.4 vs 4.2 ± 1.6 days; t=6.81, p<0.001).
Conclusion:
Undernutrition was common among children hospitalized with pulmonary infections and was significantly associated with greater clinical severity, higher complication burden, and prolonged hospitalization.
Recommendations:
Early nutritional screening and targeted nutritional support should be integrated into routine pediatric respiratory care pathways.
References
Rudan I, Boschi-Pinto C, Biloglav Z, Mulholland K, Campbell H. Epidemiology and etiology of childhood pneumonia. Bull World Health Organ. 2008 May;86(5):408-16. doi:10.2471/blt. 07.048769. https://doi.org/10.2471/BLT.07.048769
Nair H, Simões EA, Rudan I, Gessner BD, Azziz-Baumgartner E, Zhang JSF, et al; Severe Acute Lower Respiratory Infections Working Group. Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet. 2013 Apr 20;381(9875):1380-1390. doi: 10.1016/S0140-6736(12)61901-1. Epub 2013 Jan 29. PMID: 23369797; PMCID: PMC3986472.
McAllister DA, Liu L, Shi T, Chu Y, Reed C, Burrows J, et al. Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis. Lancet Glob Health. 2019 Jan;7(1):e47-e57. doi: 10.1016/S2214-109X(18)30408-X. Epub 2018 Nov 26. PMID: 30497986; PMCID: PMC6293057. https://doi.org/10.1016/S2214-109X(18)30408-X
Kirolos A, Blacow RM, Parajuli A, Welton NJ, Khanna A, Allen SJ, et al. The impact of childhood malnutrition on mortality from pneumonia: a systematic review and network meta-analysis. BMJ Glob Health. 2021 Nov;6(11):e007411. doi: 10.1136/bmjgh-2021-007411. PMID: 34848440; PMCID: PMC8634228. https://doi.org/10.1136/bmjgh-2021-007411
Caulfield LE, de Onis M, Blössner M, Black RE. Undernutrition is an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles. Am J Clin Nutr. 2004 Jul;80(1):193-8. doi:10.1093/ajcn/80.1.193. https://doi.org/10.1093/ajcn/80.1.193
Goyal JP, Kumar P, Mukherjee A, Das RR, Bhat JI, Ratageri V, et al; Acute Respiratory Infection Treatment Unit Study Group. Risk Factors for the Development of Pneumonia and Severe Pneumonia in Children. Indian Pediatr. 2021 Nov 15;58(11):1036-1039. https://doi.org/10.1007/s13312-021-2369-1
WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards are based on length/height, weight, and age. Acta Paediatr Suppl. 2006 Apr;450:76-85. doi: 10.1111/j.1651-2227.2006.tb02378.x. PMID: 16817681. https://doi.org/10.1111/j.1651-2227.2006.tb02378.x
Bloem M. The 2006 WHO child growth standards. BMJ. 2007 Apr 7;334(7596):705-6. doi: 10.1136/bmj. 39155.658843.BE. PMID: 17413142; PMCID: PMC1847861. https://doi.org/10.1136/bmj.39155.658843.BE
Topal A, Tolunay O. Effect of malnutrition on length of hospital stay in children. Turk Arch Pediatr. 2021 Jan 1;56(1):37-43. doi: 10.14744/TurkPediatriArs. 2020.46354. PMID: 34013228; PMCID: PMC8114599.
Rocha GA, Rocha EJ, Martins CV. The effects of hospitalization on the nutritional status of children. J Pediatr (Rio J). 2006 Jan-Feb;82(1):70-4. doi: 10.2223/JPED.1440. PMID: 16532151. https://doi.org/10.2223/JPED.1440
Revised WHO Classification and Treatment of Pneumonia in Children at Health Facilities: Evidence Summaries. Geneva: World Health Organization; 2014. PMID: 25535631.
Gove S. Integrated management of childhood illness by outpatient health workers: technical basis and overview. The WHO Working Group on Guidelines for Integrated Management of the Sick Child. Bull World Health Organ. 1997;75 Suppl 1(Suppl 1):7-24. PMID: 9529714; PMCID: PMC2486995.
Srivastava AD, Awasthi S, Jauhari S. Prevalence of persistent pneumonia among severe pneumonia and nutritional status as its associated risk factor: A prospective observational study among under-five children. J Family Med Prim Care. 2024 May;13(5):1911-1916. doi: 10.4103/jfmpc.jfmpc_1480_23. Epub 2024 May 24. PMID: 38948562; PMCID: PMC11213408. https://doi.org/10.4103/jfmpc.jfmpc_1480_23
Tirore LL, Abame DE, Sedoro T, Ermias D, Arega A, Tadesse T, et al. Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2-59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study. Pediatric Health Med Ther. 2021 Jul 21;12:347-357. doi: 10.2147/PHMT.S321184. PMID: 34321951; PMCID: PMC8312316. https://doi.org/10.2147/PHMT.S321184
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Dr. V Sai Savya, Dr. Sudhakar Chiluka, Dr. S Sunil Kumar

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
















