Estimation of Perfusion Index as an Objective Tool for Assessment of Analgesia During Laparoscopic Surgeries Under General Anesthesia: A Prospective Observational Study.

Authors

  • Mubasher Ahmad Bhat Associate Professor, Department of Anesthesia, GMC Srinagar, India.
  • Nidhi Breya Senior Resident, Department of Anesthesia, AIIMS JAMMU, India.
  • Rajjat Sharma Senior Resident, Department of Anesthesia, AIIMS Vijaypur, India.

DOI:

https://doi.org/10.51168/sjhrafrica.v7i2.2639

Keywords:

Perfusion Index, General Anesthesia, Laparoscopic Surgery, Heart Rate, Mean Arterial Pressure, Analgesic Monitoring

Abstract

Background:

Painful surgical stimuli during general anesthesia trigger sympathetic responses that alter heart rate (HR), mean arterial pressure (MAP), and peripheral perfusion. The Perfusion Index (PI), derived from pulse oximetry, may serve as an objective indicator of nociception and analgesic adequacy during surgery.

 Aim:

To evaluate the utility of PI as an objective tool for monitoring intraoperative analgesia during laparoscopic surgeries under general anesthesia.

 Methods:

This prospective observational study included 40 ASA Physical Status I patients aged 20–50 years undergoing elective laparoscopic surgery under general anesthesia at a tertiary care teaching hospital. PI, Pleth Variability Index (PVi), HR, and MAP were recorded at predefined intraoperative time points, including laparoscopic port insertion. An additional fentanyl bolus (0.5 µg/kg) was administered after the first port insertion. Data were analyzed using paired t-tests and Pearson correlation analysis.

 Results:

The mean age of participants was 42.5 ± 8.4 years, with females accounting for 60% of the study population. Mean PI increased significantly from 4.74 ± 1.67 at baseline to 13.61 ± 3.17 following fentanyl administration (p < 0.001). Concurrently, HR and MAP decreased significantly. PI demonstrated an inverse correlation with HR and MAP, indicating reduced sympathetic activity and improved analgesic adequacy.

 Conclusion:

PI is a reliable, objective, and non-invasive indicator of intraoperative analgesic adequacy during laparoscopic surgery under general anesthesia.

 Recommendation:

Routine use of PI monitoring alongside conventional hemodynamic parameters may improve analgesic titration during surgery. Larger multicenter studies are recommended to establish standardized PI thresholds for clinical use.

Author Biographies

Mubasher Ahmad Bhat, Associate Professor, Department of Anesthesia, GMC Srinagar, India.

MBBS, MD (Anesthesiology) Associate Professor, Department of Anesthesiology and Critical Care, Government Medical College Srinagar, Jammu and Kashmir, India.

Nidhi Breya, Senior Resident, Department of Anesthesia, AIIMS JAMMU, India.

MBBS, MD Senior Resident, Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jammu, India.

References

Gruenewald M, Dempfle A. Analgesia/nociception monitoring for opioid guidance: meta-analysis of randomized clinical trials. Minerva Anestesiol. 2017;83(2):200-213. https://doi.org/10.23736/S0375-9393.16.11602-5

Sriganesh K, Theerth KA, Reddy M, Chakrabarti D, Rao GSU. Analgesia nociception index and systemic haemodynamics during anaesthetic induction and tracheal intubation: a secondary analysis of a randomised controlled trial. Indian J Anaesth. 2019;63(2):100-105. https://doi.org/10.4103/ija.IJA_656_18

Mehandale SG, Rajasekhar P. Perfusion index as a predictor of hypotension following propofol induction: a prospective observational study. Indian J Anaesth. 2017;61(12):990-995. https://doi.org/10.4103/ija.IJA_352_17

Surekha C, Eadara VS, Satish Kumar MN. Evaluation of perfusion index as an objective tool to assess analgesia during laparoscopic surgeries under general anaesthesia. Indian J Anaesth. 2022;66(4):260-265. https://doi.org/10.4103/ija.ija_658_21

Hager H, Reddy D, Kurz A. Perfusion index: a valuable tool to assess changes in peripheral perfusion caused by sevoflurane. Anesthesiology. 2003;99:A593.

Mohamed SA, Mohamed NN, Rashwan D. Pulse co-oximetry perfusion index as a tool for acute postoperative pain assessment and its correlation to visual analogue pain score. Research and Opinion in Anesthesia and Intensive Care. 2015;2(2):62-67. https://doi.org/10.4103/2356-9115.172783

Lima A, Bakker J. Noninvasive monitoring of peripheral perfusion. Intensive Care Med. 2005;31(10):1316-1326. https://doi.org/10.1007/s00134-005-2790-2

Huiku M, Uutela K, van Gils M, Korhonen I, Kymäläinen M, Meriläinen P, et al. Assessment of surgical stress during general anaesthesia. Br J Anaesth. 2007;98(4):447-455. https://doi.org/10.1093/bja/aem004

Cannesson M, Desebbe O, Rosamel P, Delannoy B, Robin J, Bastien O, et al. Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre. Br J Anaesth. 2008;101(2):200-206. https://doi.org/10.1093/bja/aen133

Boselli E, Daniela-Ionescu M, Bégou G, Bouvet L, Dabouz R, Magnin C, et al. Prospective observational study of the non-invasive assessment of immediate postoperative pain using the analgesia nociception index (ANI). Br J Anaesth. 2013;111(3):453-459https://doi.org/10.1093/bja/aet110

Downloads

Published

2026-06-30

How to Cite

Bhat, M. A. ., Breya, N. ., & Sharma, R. . (2026). Estimation of Perfusion Index as an Objective Tool for Assessment of Analgesia During Laparoscopic Surgeries Under General Anesthesia: A Prospective Observational Study. Student’s Journal of Health Research Africa, 7(2), 10. https://doi.org/10.51168/sjhrafrica.v7i2.2639

Issue

Section

Section of Anesthesia and Surgery Research